The Seasteading Institute is seeking a Director of Operations who will help translate our world-changing vision into solid, predictable results. This individual will be responsible for a variety of key projects across all areas of our strategy, including research, communications, fundraising, event management, and more. As a member of our leadership team, the Director of Operations is also expected to help create organizational strategy and will be responsible for all internal corporate operations, including HR, finance, compliance, and facilities.
This is a paid, full-time position based in Sunnyvale, CA, likely starting in January or February. We offer excellent work-life balance benefits (including part-time telecommuting), a quality PPO health insurance plan, and a 401(k) plan in addition to other standard California state benefits.
TSI is also offering a $2500 referral bonus if you can help us find someone to fulfill the position. For more information, please see the official job description page.
The nine categories in harm to self are drug-specific mortality, drug-related mortality, drug-specific damage, drug-related damage, dependence, drug-specific impairment of mental function, drug-related impairment of mental functioning, loss of tangibles, loss of relationships, and injury. The harm to others categories are crime, environmental damage, family conflict, international damage, economic cost, and decline in community cohesion.
Overall, MCDA modelling showed alcohol was the most harmful drug (overall harm score 72), with heroin (55) and crack (54) in second and third places. Heroin, crack, and crystal meth were the most harmful drugs to the individual, whereas alcohol, heroin, and crack were the most harmful to others. The other drugs assessed followed in this order in terms of overall harm: Crystal meth (33), cocaine (27), tobacco (26), amphetamine/speed (23), cannabis (20), GHB (18), benzodiazepines (eg valium) (15), ketamine (also 15), methadone (14), mephedrone (13), butane (10), khat (9), ecstacy (9), anabolic steroids (9), LSD (7), buprenorphine (6), mushrooms (5).
Thus the new ISCD MCDA modelling showed that as well as being the most harmful drug overall, alcohol is almost three times as harmful as cocaine or tobacco. It also showed that alcohol is more than five times more harmful than mephedrone, which was recently a so-called legal high in the UK before it was made a class B controlled drug in April 2010. Ecstasy, which has had much harm-related media attention over the past two decades, is only one eighth as harmful as alcohol in this new analysis.
How Fiat Dies: 22,727 Golden Geese
28-Nov-10
The total value of all US public companies is about $13.4 trillion with a P/E of 28 which means total earnings of about $0.5 trillion. Bernanke’s printing presses make about twice as much money each year as the total earnings of all US public companies.
“Cocaine, meth, nicotine, morphine — we did the same studies with 18-MC, and it worked as well or better than ibogaine,” Glick says. “We also have data that it will be useful in treating obesity. In animals, it blocks their intake of sweet and fatty foods without affecting their nutrient intake.”
Glick and his cohorts have yet to determine whether their synthetic ibogaine has psychedelic properties. The rats, after all, aren’t talking. “You look at an animal given ibogaine, and you can’t tell if they’re hallucinating. But they look positively strange,” he says. “You give them 18-MC, and you can’t really tell. But we hope when it gets to people, it won’t produce hallucinatory effects.”
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27-Nov-10
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The 2C compounds produce a wide range of effects. Some are highly visual, while some are deeply introspective. Others enhance cognition or have primarily emotional effects. Many have few overt psychedelic effects at all. They are generally less potent and shorter acting than other more well known psychedelics.2C-B is known as a sensual, tactile drug, often referred to as an “aphrodisiac.” 2C-T-7 is called “7th-Heaven” because it tends to produce states of enlightenment. 2C-E is known as “the teacher” because it promotes optimism, thoughtfulness and creativity. 2C-I is a more traditional, overtly LSD-like psychedelic, tending to be more visual and intellectual.
“The story of the 2C compounds,” says chemist Paul Daley, co-author with Sasha Shulgin and Tania Manning of The Shulgin Index: Psychedelic Phenethylamines & Related Compounds, “really starts with the first attempts to modify known naturally occurring psychedelics, to change their activity. This began in 1949 with the creation of the first synthetic analog of mescaline.”
Mescaline, the principle active agent in peyote, was the first known psychedelic. Its use goes back over 7,000 years. It belongs to a family of compounds known as “phenethylamines,” which include the 2C family and more well-known drugs like MDMA, MDA, amphetamine, anti-depressants like Wellbutrin and Effexor, and essential amino acids like L-tyrosine. Phenethylamines are structurally close to dopamine, which is naturally occurring in the brain, and is involved with the sensing of pleasure and ‘reward.’ Phenethylamines are thought to be involved in the drive to repeat dosing with drugs such as cocaine and amphetamines, that stimulate dopamine receptors in the brain.
One of the great unsung tragedies of the “War on Drugs” (aside from the unjustified imprisonment of millions of people) is the harmful effect it has had on brain research and medical treatment. These drugs have powerful effects that could be used to investigate fundamental properties of cognition, emotion, spirituality, and perception. But because they’re illegal, very few scientists are willing to take the risks required to investigate them.
Buddhist humor
26-Nov-10
imagine a banking system, but distributed over thousands or hundreds of thousands of computers. The computers together hold a database of transactions, similar to the database clearing banks or credit card companies hold: X transferred something to Y, Y transferred the same thing to Z.
No one computer manages this database; they all run the same software, which collectively distributes the knowledge and procedures that make up this set of accounting books.
As well as this database, the computers also generate unique numbers, at a slow but adjustable rate. These unique numbers make up the only “things” that can be recorded in that transaction database. So when X is recorded as transferring a thing, it can only really transfer one of these numbers.
There aren’t many of these numbers around to begin with, because they’re so hard to create. You create them by doing the work of checking and recording the latest transactions in the database. If you do that, you get one or maybe more of the unique numbers as a byproduct.
Got that? Well, don’t worry if you didn’t, because here’s the real meat of the Bitcoins idea. Think of the unique number as coins, and of the shared database as a record of who has what coin. You can use the Bitcoin system to “pay” someone in these coins – I just record the transaction of my numbers to your computer in the global database. If the database shows that I had those Bitcoins originally, and the system successfully records the transfer, then I’ve effectively given my Bitcoins to you.